Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae

被引：111

作者：

Trotter, Caroline L. ^{[1
]}

McVernon, Jodie ^{[2
,3
]}

Ramsay, Mary E. ^{[4
]}

Whitney, Cynthia G. ^{[5
]}

Mulholland, E. Kim ^{[6
]}

Goldblatt, David ^{[7
]}

Hombach, Joachim ^{[8
]}

Kieny, Marie-Paule ^{[8
]}

机构：

[1] Univ Bristol, Dept Social Med, Bristol BS8 2PR, Avon, England

[2] Univ Melbourne, Murdoch Childrens Res Inst, Vaccine & Immunisat Res Grp, Melbourne, Vic 3010, Australia

[3] Univ Melbourne, Sch populat Hlth, Melbourne, Vic 3010, Australia

[4] Ctr Infect, Hlth Protect Agcy, Immunisat Dept, London, England

[5] Ctr Dis Control & Prevent, Natl Ctr Infect Dis, Div Bacterial & Mycot Dis, Atlanta, GA USA

[6] London Sch Hyg & Trop Med, Infect Dis Epidemiol Unit, London WC1, England

[7] UCL, Inst Child Hlth, Immunobiol Unit, London, England

[8] World Hlth Org, Initiat Vaccine Res, Geneva, Switzerland

来源：

VACCINE | 2008年 / 26卷 / 35期

关键词：

Haemophilus vaccines; meningococcal vaccines; pneumococcal vaccines;

D O I：

10.1016/j.vaccine.2008.05.073

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Conjugate vaccines exist that offer protection against disease caused by Haemophilus influenzae type b (Hib), and selected serogroups/serotypes of Neisseria meningitidis and Streptococcus pneumoniae. These vaccines are not only able to prevent serious disease, but they also provide protection against asymptomatic carriage. The resulting herd immunity effects have been striking, and have played an important role in the public health success of conjugate vaccination programmes. The aim of this paper is to review the state of the current evidence on conjugate vaccines and to identify important areas for further study, in order to inform the debate regarding the best use of these vaccines. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：4434 / 4445

页数：12

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