A Review of Biodegradable Natural Polymer-Based Nanoparticles for Drug Delivery Applications

被引：242

作者：

Idrees, Humaira ^{[1
]}

Zaidi, Syed Zohaib Javaid ^{[2
]}

Sabir, Aneela ^{[1
]}

Khan, Rafi Ullah ^{[1
,2
]}

Zhang, Xunli ^{[3
]}

Hassan, Sammer-ul ^{[3
]}

机构：

[1] Univ Punjab, Dept Polymer Engn & Technol, Lahore 54590, Pakistan

[2] Univ Punjab, Inst Chem Engn & Technol, Lahore 54000, Punjab, Pakistan

[3] Univ Southampton, Fac Engn & Phys Sci, Mech Engn, Southampton SO17 1BJ, Hants, England

来源：

NANOMATERIALS | 2020年 / 10卷 / 10期

基金：

英国经济与社会研究理事会;

关键词：

polymers; biodegradable; nanoparticles; drug delivery; pharmaceutical; HYDROXYAPATITE-POLYETHYLENE COMPOSITES; HYALURONIC-ACID NANOPARTICLES; BLOOD-BRAIN-BARRIER; CHITOSAN NANOPARTICLES; CONTROLLED-RELEASE; SERUM-ALBUMIN; IN-VITRO; ENAMEL DEMINERALIZATION; SILVER NANOPARTICLES; TARGETED DELIVERY;

D O I：

10.3390/nano10101970

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Biodegradable natural polymers have been investigated extensively as the best choice for encapsulation and delivery of drugs. The research has attracted remarkable attention in the pharmaceutical industry. The shortcomings of conventional dosage systems, along with modified and targeted drug delivery methods, are addressed by using polymers with improved bioavailability, biocompatibility, and lower toxicity. Therefore, nanomedicines are now considered to be an innovative type of medication. This review critically examines the use of natural biodegradable polymers and their drug delivery systems for local or targeted and controlled/sustained drug release against fatal diseases.

引用

页码：1 / 22

页数：22

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