A 3D Interconnected Microchannel Network Formed in Gelatin by Sacrificial Shellac Microfibers

被引：97

作者：

Bellan, Leon M. ^{[1
]}

Pearsall, Matthew ^{[1
]}

Cropek, Donald M. ^{[2
]}

Langer, Robert ^{[1
]}

机构：

[1] MIT, David H Koch Inst, Cambridge, MA 02139 USA

[2] USA, Corps Engineers, Construct Engn Res Lab, Champaign, IL 61822 USA

来源：

ADVANCED MATERIALS | 2012年 / 24卷 / 38期

关键词：

vascular; hydrogel; gelatin; shellac; microfiber; SELF-HEALING MATERIALS; MICROVASCULAR NETWORKS; VASCULAR-RESISTANCE; TISSUE; FABRICATION; HYDROGELS; SECTIONS; FLAPS;

D O I：

10.1002/adma.201200810

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

3D microfluidic networks are fabricated in a gelatin hydrogel using sacrificial melt-spun microfibers made from a material with pH-dependent solubility. The fibers, after being embedded within the gel, can be removed by changing the gel pH to induce dissolution. This process is performed in an entirely aqueous environment, avoiding extreme temperatures, low pressures, and toxic organic solvents. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

收藏

页码：5187 / 5191

页数：5

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