Magnetic Nanoparticles for Drug Delivery Applications

被引：148

作者：

Namdeo, Mini ^{[1
]}

Saxena, Sutanjay ^{[1
]}

Tankhiwale, Rasika ^{[1
]}

Bajpai, M. ^{[1
]}

Mohan, Y. M. ^{[2
]}

Bajpai, S. K. ^{[1
]}

机构：

[1] Govt Model Sci Coll, Polymer Res Lab, Dept Chem, Jabalpur 482001, Madhya Pradesh, India

[2] Sri Krishnadevaraya Univ, Dept Polymer Sci & Technol, Anantapur 515003, Andhra Pradesh, India

来源：

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | 2008年 / 8卷 / 07期

关键词：

Magnetic Nanoparticles; Targeted Drug Delivery; Magnetic Resonance Imaging; Cancer Therapy; Hyperthermia; Tumor; Nanotechnology;

D O I：

10.1166/jnn.2008.399

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In recent past magnetic nanoparticles have been explored for a number of biomedical applications due to their superparamagnetic moment with high magnetic saturation value. For these biomedical applications, magnetic nanoparticles require being monodispersed so that the individual nanoparticle has almost identical physico-chemical properties for biodistribution, bioelimination and contrast imaging potential. Further, the surface functionalization/modification of magnetic nanoparticles ultimately facilitate the protein or DNA separation, detection and magnetic resonance imaging contrast, drug delivery and hyperthermia applications. The essential goal of this review is to evaluate the recent advances of magnetic nanoparticles for tumor, brain targeting and hyperthermia applications.

引用

页码：3247 / 3271

页数：25

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