Cortactin is necessary for F-actin accumulation in pedestal structures induced by enteropathogenic Escherichia coli infection

被引：37

作者：

Cantarelli, VV

Takahashi, A

Yanagihara, I

Akeda, Y

Imura, K

Kodama, T

Kono, G

Sato, Y

Iida, T

Honda, T

机构：

[1] Osaka Univ, Microbial Dis Res Inst, Dept Bacterial Infect, Suita, Osaka 5650871, Japan

[2] Univ Tokushima, Sch Med, Dept Nutr, Tokushima 7708503, Japan

[3] Lab Weinmann LTDA, Porto Alegre, RS, Brazil

来源：

INFECTION AND IMMUNITY | 2002年 / 70卷 / 04期

关键词：

D O I：

10.1128/IAI.70.4.2206-2209.2002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Cortactin and the translocated intimin receptor, Tir, interacted with each other in pedestal formation in HeLa cells infected with enteropathogenic Escherichia coli (SPEC). Cortactin is shown to be necessary for organizing actin pedestals in response to SPEC, based on the expression of green fluorescent protein-fused cortactin derivatives in HeLa cells.

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页码：2206 / 2209

页数：4

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