The conformation of ribosomes and rRNA

被引：7

作者：

Moore, PB ^{[1
]}

机构：

[1] YALE UNIV,DEPT MOL BIOPHYS & BIOCHEM,NEW HAVEN,CT 06511

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1997年 / 7卷 / 03期

关键词：

D O I：

10.1016/S0959-440X(97)80049-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

During the past 18 months, electron microscopists have published two reconstructions of the Escherichia coli ribosome, independently derived from images of unstained particles. The resolutions of their images are 20-25 Angstrom - much higher than any previously available. During the same time, NMR spectroscopists have provided an atomic-resolution model for the A-site region of 16S rRNA complexed with paromomycin that explains much of what is known about the interaction of aminoglycoside antibiotics with ribosomes. (C) Current Biology Ltd.

引用

页码：343 / 347

页数：5

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