Solvent-drop grinding: green polymorph control of cocrystallisation

被引：361

作者：

Trask, AV

Motherwell, WDS

Jones, W

机构：

[1] Univ Cambridge, Dept Chem, Pfizer Inst Pharmaceut Mat Sci, Cambridge CB2 1EW, England

[2] Cambridge Crystallog Data Ctr, Cambridge CB2 1EZ, England

来源：

CHEMICAL COMMUNICATIONS | 2004年 / 07期

关键词：

D O I：

10.1039/b400978a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

By grinding with a minimal addition of a solvent of appropriate polarity, control over the polymorphic outcome of a novel cocrystallisation involving the model pharmaceutical compound caffeine may be achieved.

引用

页码：890 / 891

页数：2