Sample pretreatment on microfabricated devices

被引：144

作者：

Lichtenberg, J ^{[1
]}

de Rooij, NF ^{[1
]}

Verpoorte, E ^{[1
]}

机构：

[1] Univ Neuchatel, SAMLAB, Inst Microtechnol, CH-2007 Neuchatel, Switzerland

来源：

TALANTA | 2002年 / 56卷 / 02期

关键词：

sample pretreatment; microfabricated devices; miniaturized total analysis systems; sample preparation; purification; filtering; preconcentration; PCR; dialysis; labeling;

D O I：

10.1016/S0039-9140(01)00593-8

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The integration of sample pretreatment into microfluidic devices represents one of the remaining hurdles towards achieving true miniaturized total analysis systems (muTAS). The challenge is made more complex by the enormous variation in samples to be analyzed. Moreover, the pretreatment technique has to be compatible with the analysis device to which it is coupled in terms of time, reagent and power consumption, as well as sample volume. This review provides a thorough overview of the developments in this field to date. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：233 / 266

页数：34

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