Copper-catalysed aerobic oxidation of alcohols using fluorous biphasic catalysis

被引：165

作者：

Ragagnin, G

Betzemeier, B

Quici, S

Knochel, P

机构：

[1] Univ Munich, Dept Chem, D-81377 Munich, Germany

[2] CNR, Ctr Sintesi & Stereochim Speciali Sistemi Organ, Dipartimento Chim Organ & Ind, I-20133 Milan, Italy

来源：

TETRAHEDRON | 2002年 / 58卷 / 20期

关键词：

alcohols oxidation; TEMPO; fluorinated copper ligands; cyclohexanols; fluorous catalysis;

D O I：

10.1016/S0040-4020(02)00250-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A copper(I) catalysed and TEMPO mediated fluorous biphasic oxidation of primary, secondary, allylic and benzylic alcohols with oxygen in the presence of a bipyridine ligand bearing perfluorinated ponytails is described. High chemoselectivities are observed in the oxidation of substituted cyclohexanols (substituted axial cyclohexanols react 6-8 times faster than the corresponding equatorial cyclohexanols). (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：3985 / 3991

页数：7

共 41 条

[1] OXIDATION OF DIOLS WITH ALKALI HYPOCHLORITES CATALYZED BY OXAMMONIUM SALTS UNDER 2-PHASE CONDITIONS [J].