DAVID-WS: a stateful web service to facilitate gene/protein list analysis

被引:1033
作者
Jiao, Xiaoli [1 ]
Sherman, Brad T. [1 ]
Huang, Da Wei [1 ]
Stephens, Robert [2 ]
Baseler, Michael W. [3 ]
Lane, H. Clifford [4 ]
Lempicki, Richard A. [1 ]
机构
[1] NCI, Lab Immunopathogenesis & Bioinformat, Frederick, MD 21702 USA
[2] NCI, Adv Biomed Comp Ctr, Frederick, MD 21702 USA
[3] NCI, SAIC Frederick Inc, Clin Serv Program, Frederick, MD 21702 USA
[4] NIAID, Immunogenet Lab, NIH, Bethesda, MD 20892 USA
基金
美国国家卫生研究院;
关键词
RESOURCES; DATABASE;
D O I
10.1093/bioinformatics/bts251
中图分类号
Q5 [生物化学];
学科分类号
070307 [化学生物学];
摘要
The database for annotation, visualization and integrated discovery (DAVID), which can be freely accessed at http://david.abcc.ncifcrf.gov/, is a web-based online bioinformatics resource that aims to provide tools for the functional interpretation of large lists of genes/proteins. It has been used by researchers from more than 5000 institutes worldwide, with a daily submission rate of similar to 1200 gene lists from similar to 400 unique researchers, and has been cited by more than 6000 scientific publications. However, the current web interface does not support programmatic access to DAVID, and the uniform resource locator (URL)-based application programming interface (API) has a limit on URL size and is stateless in nature as it uses URL request and response messages to communicate with the server, without keeping any state-related details. DAVID-WS (web service) has been developed to automate user tasks by providing stateful web services to access DAVID programmatically without the need for human interactions.
引用
收藏
页码:1805 / 1806
页数:2
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