Genomewide Association Studies and Common Disease - Realizing Clinical Utility

被引:27
作者
Fugger, Lars [1 ,2 ]
McVean, Gil [3 ]
Bell, John I. [4 ]
机构
[1] Univ Oxford, Weatherall Inst Med, Oxford, England
[2] Univ Oxford, Nuffield Dept Clin Neurosci, Oxford, England
[3] Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England
[4] Univ Oxford, Off Regius Prof Med, Oxford, England
基金
英国惠康基金; 英国医学研究理事会;
关键词
D O I
10.1056/NEJMp1212285
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:2370 / 2371
页数:2
相关论文
共 5 条
[1]   TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis [J].
Gregory, Adam P. ;
Dendrou, Calliope A. ;
Attfield, Kathrine E. ;
Haghikia, Aiden ;
Xifara, Dionysia K. ;
Butter, Falk ;
Poschmann, Gereon ;
Kaur, Gurman ;
Lambert, Lydia ;
Leach, Oliver A. ;
Proemel, Simone ;
Punwani, Divya ;
Felce, James H. ;
Davis, Simon J. ;
Gold, Ralf ;
Nielsen, Finn C. ;
Siegel, Richard M. ;
Mann, Matthias ;
Bell, John I. ;
McVean, Gil ;
Fugger, Lars .
NATURE, 2012, 488 (7412) :508-+
[2]   Novel systemic drugs under investigation for the treatment of psoriasis [J].
Gudjonsson, Johann E. ;
Johnston, Andrew ;
Ellis, Charles N. .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2012, 67 (01) :139-147
[3]   Treating Human Autoimmunity: Current Practice and Future Prospects [J].
Rosenblum, Michael D. ;
Gratz, Iris K. ;
Paw, Jonathan S. ;
Abbas, Abul K. .
SCIENCE TRANSLATIONAL MEDICINE, 2012, 4 (125)
[4]   Type 2 diabetes and obesity: genomics and the clinic [J].
Travers, Mary E. ;
McCarthy, Mark I. .
HUMAN GENETICS, 2011, 130 (01) :41-58
[5]   Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study [J].
Voight, Benjamin F. ;
Peloso, Gina M. ;
Orho-Melander, Marju ;
Frikke-Schmidt, Ruth ;
Barbalic, Maja ;
Jensen, Majken K. ;
Hindy, George ;
Holm, Hilma ;
Ding, Eric L. ;
Johnson, Toby ;
Schunkert, Heribert ;
Samani, Nilesh J. ;
Clarke, Robert ;
Hopewell, Jemma C. ;
Thompson, John F. ;
Li, Mingyao ;
Thorleifsson, Gudmar ;
Newton-Cheh, Christopher ;
Musunuru, Kiran ;
Pirruccello, James P. ;
Saleheen, Danish ;
Chen, Li ;
Stewart, Alexandre F. R. ;
Schillert, Arne ;
Thorsteinsdottir, Unnur ;
Thorgeirsson, Gudmundur ;
Anand, Sonia ;
Engert, James C. ;
Morgan, Thomas ;
Spertus, John ;
Stoll, Monika ;
Berger, Klaus ;
Martinelli, Nicola ;
Girelli, Domenico ;
McKeown, Pascal P. ;
Patterson, Christopher C. ;
Epstein, Stephen E. ;
Devaney, Joseph ;
Burnett, Mary-Susan ;
Mooser, Vincent ;
Ripatti, Samuli ;
Surakka, Ida ;
Nieminen, Markku S. ;
Sinisalo, Juha ;
Lokki, Marja-Liisa ;
Perola, Markus ;
Havulinna, Aki ;
de Faire, Ulf ;
Gigante, Bruna ;
Ingelsson, Erik .
LANCET, 2012, 380 (9841) :572-580