The distribution of cerebral activity related to visuomotor coordination indicating perceptual and executional specialization

被引:42
作者
de Jong, BM
Frackowiak, RSJ
Willemsen, ATM
Paans, AMJ
机构
[1] Univ Groningen Hosp, Dept Neurol, NL-9700 RB Groningen, Netherlands
[2] Hammersmith Hosp, MRC, Cyclotron Unit, London W12 0HS, England
[3] Inst Neurol, Wellcome Dept Cognit Neurol, London WC1N 3BG, England
[4] Univ Groningen Hosp, PET Ctr, Groningen, Netherlands
来源
COGNITIVE BRAIN RESEARCH | 1999年 / 8卷 / 01期
基金
英国惠康基金;
关键词
visuomotor control; coordinate transformation; PET; visual area V1; posterior parietal cortex; premotor cortex;
D O I
10.1016/S0926-6410(99)00005-1
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
The distribution of increased regional cerebral blood flow (rCBF) related to visuomotor coordination was studied by means of positron emission tomography (PET) in normal subjects. An experimental condition, in which a vertically presented zigzag figure had to be copied in a horizontal orientation, was compared with a control condition in which the same horizontal drawing was made, guided by a horizontally presented example. Cognitive components dealing with the mismatch in visual orientation resulted in activation of (i) right dorsal premotor cortex, (ii) right posterior parietal cortex, (iii) visual cortex (area V1) and (iv) left fusiform gyrus. In a second experiment, conditions were compared in which the same horizontal zigzag figure was copied in either a vertical or a horizontal orientation. Now, the motor components of the transformation of orientation appeared to be associated only with left premotor cortex activation. The differential distribution of activations is regarded to reflect the selective effort to cope with either the visual or the motor component of spatial incongruity, and indicates specialization for perceptual and executive components in visuomotor control. We propose that the perceptual component of visuomotor transformation in our experiment relates to a realignment of the coordinates of a percept to an internally defined coordinate system. The executive component relates to guidance of movement within an internal representation of space. In a preceding behavioural experiment, a majority of patients with Parkinson's disease (PD) failed on the task in which they had to make a horizontal copy of a vertically presented picture. This finding may suggest a deficit in the maintenance of an internal spatial representation to guide movement. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:45 / 59
页数:15
相关论文
共 94 条
[31]   Cortical projections of area V2 in the Macaque [J].
Gattass, R ;
Sousa, APB ;
Mishkin, M ;
Ungerleider, LG .
CEREBRAL CORTEX, 1997, 7 (02) :110-129
[32]   HIGHER-ORDER MOTOR CONTROL [J].
GEORGOPOULOS, AP .
ANNUAL REVIEW OF NEUROSCIENCE, 1991, 14 :361-377
[33]  
GEORGOPOULOS AP, 1982, J NEUROSCI, V2, P1527
[34]   PREPARATION OF VISUALLY CUED ARM MOVEMENTS IN MONKEY - INVOLVEMENT OF INFERIOR PARIETAL CORTEX [J].
GODSCHALK, M ;
LEMON, RN .
BRAIN BEHAVIOR AND EVOLUTION, 1989, 33 (2-3) :122-126
[35]   THE INVOLVEMENT OF MONKEY PREMOTOR CORTEX NEURONS IN PREPARATION OF VISUALLY CUED ARM MOVEMENTS [J].
GODSCHALK, M ;
LEMON, RN ;
KUYPERS, HGJM ;
VANDERSTEEN, J .
BEHAVIOURAL BRAIN RESEARCH, 1985, 18 (02) :143-157
[36]   SEPARATE VISUAL PATHWAYS FOR PERCEPTION AND ACTION [J].
GOODALE, MA ;
MILNER, AD .
TRENDS IN NEUROSCIENCES, 1992, 15 (01) :20-25
[37]   PALLIDOTOMY INCREASES ACTIVITY OF MOTOR ASSOCIATION CORTEX IN PARKINSONS-DISEASE - A POSITRON EMISSION TOMOGRAPHIC STUDY [J].
GRAFTON, ST ;
WATERS, C ;
SUTTON, J ;
LEW, MF ;
COULDWELL, W .
ANNALS OF NEUROLOGY, 1995, 37 (06) :776-783
[38]   HUMAN FUNCTIONAL-ANATOMY OF VISUALLY GUIDED FINGER MOVEMENTS [J].
GRAFTON, ST ;
MAZZIOTTA, JC ;
WOODS, RP ;
PHELPS, ME .
BRAIN, 1992, 115 :565-587
[39]   Functional anatomy of pointing and grasping in humans [J].
Grafton, ST ;
Fagg, AH ;
Woods, RP ;
Arbib, MA .
CEREBRAL CORTEX, 1996, 6 (02) :226-237
[40]   THE ROLE OF PREMOTOR CORTEX AND THE SUPPLEMENTARY MOTOR AREA IN THE TEMPORAL CONTROL OF MOVEMENT IN MAN [J].
HALSBAND, U ;
ITO, N ;
TANJI, J ;
FREUND, HJ .
BRAIN, 1993, 116 :243-266