Synthesis of 2-amino-1,4-dihydro-4-quinolinones and diaminomethylene Meldrum's acids derivatives as potential potassium channel openers

被引：8

作者：

Erb, B

Rigo, B

Pirotte, B

Couturier, D

机构：

[1] Ecole Hautes Etud Ind, Lab Ingn Mol, F-59046 Lille, France

[2] Ctr Hosp Univ, Lab Chim Pharmaceut, B-4000 Liege, Belgium

[3] Univ Sci & Technol Lille, Lab Ingn Mol, F-59655 Villeneuve Dascq, France

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2002年 / 39卷 / 01期

关键词：

D O I：

10.1002/jhet.5570390102

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

Starting from 5-bismethylthiomethylene Meldrum's acid, the synthesis of 5-diaminomethylene Meldrum's acids and 2-aminoquinolone derivatives, structurally related to potassium channels openers pinacidil and diazoxide, is described.

引用

页码：15 / 28

页数：14

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