Ultrastable, Highly Fluorescent, and Water-Dispersed Silicon-Based Nanospheres as Cellular Probes

被引：161

作者：

He, Yao ^{[2
,3
,4
]}

Kang, Zhen-Hui ^{[2
,3
,4
]}

Li, Quan-Song ^{[2
,3
]}

Tsang, Chi Him A. ^{[2
,3
]}

Fan, Chun-Hai ^{[1
]}

Lee, Shuit-Tong ^{[2
,3
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China

[2] City Univ Hong Kong, COSDAF, Hong Kong, Hong Kong, Peoples R China

[3] City Univ Hong Kong, Dept Phys & Mat Sci, Hong Kong, Hong Kong, Peoples R China

[4] Soochow Univ, FUNSOM, Suzhou 215123, Jiangsu, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 01期

关键词：

fluorescent probes; nanostructures; photostability; quantum dots; silicon; SEMICONDUCTOR QUANTUM DOTS; CDTE NANOCRYSTALS; LIVE CELLS; NANOPARTICLES; PHOTOLUMINESCENCE; CYTOTOXICITY; BIOCOMPATIBILITY; LABELS; CDSE;

D O I：

10.1002/anie.200802230

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) In silico to in vivo: The design strategy for silicon-based fluorescent nanospheres with controllable sizes was based on the results of theoretical calculations. These nanospheres are fully water dispersible, highly photoluminescent, extremely photostable, and suitably biocompatible. Cell imaging results further demonstrate the nanospheres are remarkably efficacious for real-time and long-term cell monitoring (see picture). © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：128 / 132

页数：5

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