Effect of subinhibitory concentrations of cumin (Cuminum cyminum L.) seed essential oil and alcoholic extract on the morphology, capsule expression and urease activity of Klebsiella pneumoniae

被引：65

作者：

Derakhshan, Safoura ^{[1
]}

Sattari, Morteza ^{[1
]}

Bigdeli, Mohsen ^{[2
]}

机构：

[1] Tarbiat Modares Univ, Sch Med Sci, Dept Bacteriol, Tehran, Iran

[2] Agr Res Ctr, Tehran, Iran

来源：

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 2008年 / 32卷 / 05期

关键词：

Antibacterial effect; Klebsiella pneumoniae; Cuminum cyminum L;

D O I：

10.1016/j.ijantimicag.2008.05.009

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Cuminum cyminum L., commonly known as cumin, is a plant with a considerable reputation. The aim of this work was to study the activity of cumin seed essential oil and alcoholic extract against Klebsiella pneumoniae ATCC 13883 and clinical K. pneumoniae isolates by evaluating the effect of subminimum inhibitory concentrations (sub-MICs) on cell morphology, capsule expression and urease activity. Growth of K. pneumoniae strains exposed to sub-MICs of C. cyminum extracts resulted in cell elongation and repression of capsule expression. Urease activity was decreased. The major constituent of the oil determined by gas chromatography/mass spectrometry was cumin aldehyde. (C) 2008 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

引用

页码：432 / 436

页数：5

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