Copper(II) complexes of blood pressure active drugs

被引:18
作者
Bontchev, PR [1 ]
Pantcheva, IN [1 ]
机构
[1] Univ Sofia, Fac Chem, Sofia 1164, Bulgaria
关键词
D O I
10.1023/A:1013466529495
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
The interaction of copper(II) with medications, used for the regulation of arterial blood pressure, has been studied and discussed. The drugs include antihypotensives and antihypertensives of different types: beta-blockers, vasodilators, ACE-inhibitors and diuretics. The paper summarizes the results obtained for the characterization of the complexation processes and determination of the structure and properties of the complexes formed.
引用
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页码:1 / 21
页数:21
相关论文
共 96 条
[1]  
ABRAGAM A, 1970, ELECTRON PARAMAGNETI, P506
[2]  
ALEXIEV N, 1991, Patent No. 51486
[3]  
[Anonymous], P 12 INT C COORD CHE
[4]   APOMETALLOTHIONEIN IN RAT-LIVER [J].
APOSTOLOVA, M ;
BONTCHEV, PR ;
NACHEV, C ;
SIRAKOVA, I .
JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1993, 620 (02) :191-197
[5]  
Apostolova M., 1993, Comptes Rendus de l'Academie Bulgare des Sciences, V46, P75
[6]   METALLOTHIONEINS IN SPONTANEOUSLY HYPERTENSIVE RAT-LIVER [J].
APOSTOLOVA, M ;
BONTCHEV, PR ;
NACHEV, C ;
SIRAKOVA, I .
JAPANESE JOURNAL OF MEDICAL SCIENCE & BIOLOGY, 1992, 45 (04) :185-198
[7]   New competitive enzyme-linked immunosorbent assay for determination of metallothionein in tissue and sera [J].
Apostolova, M ;
Nachev, C ;
Koleva, M ;
Bontchev, PR ;
Kehaiov, I .
TALANTA, 1998, 46 (02) :325-333
[8]  
Apostolova MD, 1997, J TRACE ELEM MED BIO, V11, P1
[9]   Antioxidant and prooxidant properties of captopril and enalapril [J].
Bartosz, M ;
Kedziora, J ;
Bartosz, G .
FREE RADICAL BIOLOGY AND MEDICINE, 1997, 23 (05) :729-735
[10]  
BONDREAUX EA, 1976, THEORY APPL MOL PARA