The biochemistry, metabolism and inherited defects of the pentose phosphate pathway: A review

被引：234

作者：

Wamelink, M. M. C. ^{[1
]}

Struys, E. A. ^{[1
]}

Jakobs, C. ^{[1
]}

机构：

[1] Vrije Univ Amsterdam Med Ctr, Metab Unit, Dept Clin Chem, NL-1081 HV Amsterdam, Netherlands

来源：

JOURNAL OF INHERITED METABOLIC DISEASE | 2008年 / 31卷 / 06期

关键词：

D O I：

10.1007/s10545-008-1015-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The recent discovery of two defects (ribose-5-phosphate isomerase deficiency and transaldolase deficiency) in the reversible part of the pentose phosphate pathway (PPP) has stimulated interest in this pathway. In this review we describe the functions of the PPP, its relation to other pathways of carbohydrate metabolism and an overview of the metabolic defects in the reversible part of the PPP.

引用

页码：703 / 717

页数：15

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