New Guaiane Sesquiterpenes and Furanocoumarins from Notopterygium incisum

被引：25

作者：

Wu, Shi-Biao

Zhao, Yun

Fan, Hui

Hu, Ying-He

Hamann, Mark T. ^{[2
,3
]}

Peng, Jiang-Nan ^{[2
,3
]}

Starks, Courtney M. ^{[4
]}

O'Neil-Johnson, Mark ^{[4
]}

Hu, Jin-Feng ^{[1
,4
]}

机构：

[1] E China Normal Univ, Dept Nat Prod Chem Genet Res, Key Lab Brain Funct Genom, Minist Educ, Shanghai 200062, Peoples R China

[2] Univ Mississippi, Dept Pharmacognosy, University, MS 38677 USA

[3] Univ Mississippi, Sch Pharm, Natl Ctr Dev Nat Prod, University, MS 38677 USA

[4] Sequoia Sci Inc, St Louis, MO USA

来源：

PLANTA MEDICA | 2008年 / 74卷 / 15期

关键词：

Notopterygium incisum Ting ex H. T. Chang; Apiaceae; structure elucidation; guaiane sesquiterpenes; incisumdiols; furanocoumarins;

D O I：

10.1055/s-0028-1088326

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

In addition to twenty-nine known compounds, two new guaiane sesquiterpenes and two new furanocoumarins were isolated from the chloroform extract of the rhizomes of Notopterygium incisum. The new structures were elucidated by means of spectroscopic methods including 2D NMR techniques and mass spectrometry to be 8 beta-acetoxy-4 alpha,6 alpha-dihydroxy-1 alpha,5 alpha(H)-guai-9-ene (incisumdiol A, 1), 4 alpha,6 alpha-dihydroxy-1 alpha,5 alpha(H)guai-9-ene (incisumdiol B, 2), 5-[(2E,5Z)-7-hydroxy-3,7-dimethyl-2,5-octadienoxy]psoralene (3) and 5-[(2,5)-epoxy-3-hydroxy-3,7-dimethyl-6-octenoxy]psoralene (4).

引用

页码：1812 / 1817

页数：6

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