Reaction of N-[bis(methylthio)methylene]glycinates with electron deficient alkynes, synthesis of (Z)-alpha,beta-didehydroglutamic acid derivatives

被引：11

作者：

AlvarezIbarra, C

Csaky, AG

Ortega, EM

delaMorena, MJ

Quiroga, ML

机构：

[1] Depto. de Quim. Orgánica I, Facultad de Química, Universidad Complutense

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 25期

关键词：

D O I：

10.1016/S0040-4039(97)00913-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The addition of either the alkaline enolates of the glycinates 1 or their naked enolates to electron defficient alkynes allows for the synthesis of substituted (Z)-alpha,beta-didehydroglutamic acid derivatives 7 via a Michael addition/1,3-prototropic rearrangement sequence. (C) 1997 Elsevier Science Ltd.

引用

页码：4501 / 4502

页数：2