Enhanced asymmetric induction in cycloadditions to bridgehead-chiral vinyl dioxazaborocines

被引：37

作者：

Davies, CD

Marsden, SP ^{[1
]}

Stokes, ESE

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England

[2] AstraZeneca, Macclesfield SK10 4TG, Cheshire, England

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 21期

基金：

英国工程与自然科学研究理事会;

关键词：

asymmetric synthesis; boron and compounds; cycloaddition; isoxazolines; nitrile oxides; nitrones;

D O I：

10.1016/S0040-4039(00)00571-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Vinyl dioxazaborocines 5 with asymmetric centres on the nitrogen bridgehead substituent have been prepared and assayed in nitrile oxide and nitrone cycloadditions, giving asymmetric inductions of up to 70 and 74% ee, respectively. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：4229 / 4233

页数：5

共 10 条

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