Chiral vinyl dioxazaborocines in synthesis:: Asymmetric synthesis of 5-substituted Δ2-isoxazolines via nitrile oxide cycloaddition

被引：29

作者：

Davies, CD

Marsden, SP ^{[1
]}

Stokes, ESE

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England

[2] Zeneca Pharmaceut, Macclesfield SK10 4TG, Cheshire, England

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 46期

基金：

英国工程与自然科学研究理事会;

关键词：

asymmetric synthesis; boron and compounds; cycloaddition; isoxazolines; nitrile oxides;

D O I：

10.1016/S0040-4039(98)01851-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Vinyl dioxazaborocines 1a-c have been subjected to 1,3-dipolar cycloadditions with benzonitrile oxide. The products are enantiomerically enriched fi-substituted Delta(2)-isoxazolines 2a-c. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：8513 / 8516

页数：4

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