Synthesis of tricyclic aryl spiroacetals related to the papulacandins

被引：12

作者：

Brimble, MA

Robinson, SG

机构：

来源：

TETRAHEDRON | 1996年 / 52卷 / 28期

关键词：

D O I：

10.1016/0040-4020(96)00492-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient synthesis of aryl spiroacetals related to the antifungal agents, the papulacandins, is reported. The synthetic methodology involves the addition of ortho-lithiated diethylbenzamides to lactones followed by acid catalysed cyclization of the resultant keto-alcohols. Copyright (C) 1996 Elsevier Science Ltd

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页码：9553 / 9562

页数：10

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