High resolution scanning force microscopy of cardiac myocytes

被引:16
作者
Davis, JJ
Hill, HAO
Powell, T
机构
[1] Univ Oxford, Inorgan Chem Lab, Oxford OX1 3RQ, England
[2] Univ Oxford, Physiol Lab, Oxford OX1 3PT, England
基金
英国工程与自然科学研究理事会; 英国生物技术与生命科学研究理事会;
关键词
atomic force microscopy; cardiac myocytes; T-tubules; sarcolemma;
D O I
10.1006/cbir.2001.0813
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The advent of scanning probe microscopy has introduced a powerful new method of probing the structural features of biological specimens. In this study, high resolution atomic force microscopy micrographs of single, isolated, cardiac myocytes are presented. Significantly. our images show not only the features to be expected of the external sarcolemma, but also resolve sub-surface features. including the striated pattern of the contractile proteins and their associated sarcoplasmic reticulum and mitochondria. (C) 2001 Academic Press.
引用
收藏
页码:1271 / 1277
页数:7
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