Asymmetric synthesis of diversely substituted N-hydroxypyrrolidines using cycloadditions with chiral nitrone enolate/ylids

被引：13

作者：

Hanessian, S ^{[1
]}

Bayrakdarian, M ^{[1
]}

机构：

[1] Univ Montreal, Dept Chem, Montreal, PQ H3C 3J7, Canada

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 06期

基金：

加拿大自然科学与工程研究理事会;

关键词：

1,3-dipolar cycloaddition; pyrrolidine scaffold;

D O I：

10.1016/S0040-4039(01)02305-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A stereoselective synthesis of diversely substituted N-hydroxypyrrolidines is reported, based on the cycloaddition reaction of chiral non-racemic nitrone ylids with a variety of a,p-unsaturated esters. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：967 / 971

页数：5

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