pH dependent multifunctional and multiply-configurable logic gate systems based on small molecule G-quadruplex DNA recognition

被引:24
作者
Bhowmik, Sudipta [1 ,2 ]
Das, Rabindra Nath [2 ]
Parasar, Bibudha [2 ]
Dash, Jyotirmayee [1 ,2 ]
机构
[1] Indian Assoc Cultivat Sci, Dept Organ Chem, Kolkata 700032, India
[2] Indian Inst Sci Educ & Res Kolkata, Dept Chem Sci, Mohanpur 741252, W Bengal, India
关键词
DISPLACEMENT ASSAY; LIGANDS; COMPUTATION; DEOXYRIBOZYME; CIRCUITS;
D O I
10.1039/c3cc38888c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A variety of logic operations such as XNOR, NOR, AND, NAND, NOT have been designed with pH as an external modulator by choosing thiazole orange (TO) and a c-kit2 promoter quadruplex as two inputs and fluorescence signals of pyridyl bis-indole amide (PBIA) and TO as two outputs.
引用
收藏
页码:1817 / 1819
页数:3
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