Three-dimensional real-time in vivo magnetic particle imaging

被引：598

作者：

Weizenecker, J. ^{[1
]}

Gleich, B. ^{[1
]}

Rahmer, J. ^{[1
]}

Dahnke, H. ^{[1
]}

Borgert, J. ^{[1
]}

机构：

[1] Philips Res Europe Hamburg, Sector Med Imaging Syst, D-22335 Hamburg, Germany

来源：

PHYSICS IN MEDICINE AND BIOLOGY | 2009年 / 54卷 / 05期

关键词：

AXIAL SCANNING TOMOGRAPHY;

D O I：

10.1088/0031-9155/54/5/L01

中图分类号：

R318 [生物医学工程];

学科分类号：

100103 [病原生物学];

摘要：

Magnetic particle imaging (MPI) is a new tomographic imaging method potentially capable of rapid 3D dynamic imaging of magnetic tracer materials. Until now, only dynamic 2D phantom experiments with high tracer concentrations have been demonstrated. In this letter, first in vivo 3D real-time MPI scans are presented revealing details of a beating mouse heart using a clinically approved concentration of a commercially available MRI contrast agent. A temporal resolution of 21.5 ms is achieved at a 3D field of view of 20.4 x 12 x 16.8 mm(3) with a spatial resolution sufficient to resolve all heart chambers. With these abilities, MPI has taken a huge step toward medical application.

引用

页码：L1 / L10

页数：10

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