The stereoselective cyclopropanation of chiral allylic alcohols using a chiral dioxaborolane ligand:: A new route to anti-cyclopropylmethanol derivatives

被引：12

作者：

Charette, AB ^{[1
]}

Lebel, H ^{[1
]}

Gagnon, A ^{[1
]}

机构：

[1] Univ Montreal, Dept Chim, Montreal, PQ H37 3J7, Canada

来源：

TETRAHEDRON | 1999年 / 55卷 / 29期

关键词：

alcohols; cyclopropanation; cyclopropanes; zinc and compounds;

D O I：

10.1016/S0040-4020(99)00448-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The diastereoselective cyclopropanation reaction of allylic alcohols in the presence of the chiral dioxaborolane ligand 1 was studied. Unprecedently high anti-selectivities were obtained with E-olefins when 2.2 equivalents of bis(iodomethyl)zinc and 1.1 equivalent of 1 were used. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：8845 / 8856

页数：12

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