Simultaneous multiwavelength laminar optical tomography

被引：18

作者：

Burgess, Sean A. ^{[1
]}

Bouchard, Matthew B.

Yuan, Baohong

Hillman, Elizabeth M. C.

机构：

[1] Columbia Univ, Lab Funct Opt Imaging, Dept Biomed Engn, New York, NY 10027 USA

来源：

OPTICS LETTERS | 2008年 / 33卷 / 22期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1364/OL.33.002710

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Spatially resolved reflectance measurements can be used to characterize the depth-resolved optical properties of superficial tissues. However, until now, rapid acquisition of multiwavelength data has been hindered by multiplexing problems. We report on a novel multiwavelength laminar optical tomography system capable of acquiring data from multiple source-detector separations at three wavelengths simultaneously. Such data can allow in vivo depth-resolved spectroscopic imaging of absorbers, such as oxy- and deoxyhemoglobin, or of multiple fluorophores, that is unaffected by motion artifacts at frame rates exceeding 100 Hz. The system design and phantom validation studies are presented. (C) 2008 Optical Society of America

引用

页码：2710 / 2712

页数：3

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