The medullary subnucleus reticularis dorsalis (SRD) as a key link in both the transmission and modulation of pain signals

被引：107

作者：

Villanueva, L

Bouhassira, D

LeBars, D

机构：

[1] INSERM, 75014, Paris, U-161, 2, Rue d'Alésia

来源：

PAIN | 1996年 / 67卷 / 2-3期

关键词：

reticular formation; brainstem; dorsal horn; thalamus; dorsal columns; nociception;

D O I：

10.1016/0304-3959(96)03121-1

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

The involvement of the dorsal part of the caudal medulla in both the transmission and modulation of pain is supported by recent electrophysiological and anatomical data. In this review, we analyse the features of a well-delimited area within the caudal-most aspect of the medulla, the subnucleus reticularis dorsalis (SRD) which plays a specific role in processing cutaneous and visceral nociceptive inputs. From a general viewpoint, the reciprocal connections between the caudal medulla and spinal cord suggest that this area is an important link in feedback loops which regulate spinal outflow. Moreover, the existence of SRD-thalamic connections put a new light on the role of spino-reticulo-thalamic circuits in pain transmission.

引用

页码：231 / 240

页数：10

共 114 条

[11] EFFECTS OF SYSTEMIC MORPHINE UPON A-DELTA-FIBER AND C-FIBER EVOKED ACTIVITIES OF SUBNUCLEUS RETICULARIS DORSALIS NEURONS IN THE RAT MEDULLA [J].