Multidrug resistance is mediated by large plasmids carrying a class 1 integron in the emergent Salmonella enterica serotype [4,5,12:i:-]

被引：163

作者：

Guerra, B ^{[1
]}

Soto, SM ^{[1
]}

Argüelles, JM ^{[1
]}

Mendoza, MC ^{[1
]}

机构：

[1] Univ Oviedo, Fac Med, Dept Biol Func, Area Microbiol, E-33006 Oviedo, Spain

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 04期

关键词：

D O I：

10.1128/AAC.45.4.1305-1308.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A multidrug-resistant Salmonella enterica serotype [4,5,12:i:-] clone carried a class 1 integron harboring dfrA12. and aadA2 gene cassettes and bla(TEM-1), aac(3)-IV, cmlA1, and tetA genes located in large plasmids of about 140 kb (carrying spy) or 120 kb (lacking spy). Several segregants, lacking multidrug resistance, contained a plasmid smaller than the parental one and no longer hybridized with probes for the lost resistances. The genes mediating resistance to ampicillin, chloramphenicol, and tetracycline in the [4,5,12:i:-] clone are different from those found in the pentadrug-resistant serotype Typhimurium DT104 clone.

引用

页码：1305 / 1308

页数：4

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