Systemic lupus erythematosus and "lupus dyslipoproteinemia"

被引：76

作者：

de Carvalho, Jozelio Freire ^{[1
,2
]}

Bonfa, Eloisa ^{[1
,2
]}

Borba, Eduardo Ferreira ^{[1
,2
]}

机构：

[1] Univ Sao Paulo, Fac Med, Div Rheumatol, BR-01246903 Sao Paulo, Brazil

[2] Univ Sao Paulo, Fac Med, Hosp Clin, BR-01246903 Sao Paulo, Brazil

来源：

AUTOIMMUNITY REVIEWS | 2008年 / 7卷 / 03期

关键词：

systemic lupus erythematosus; lipoprotein; dyslipoproteinemia; atherosclerosis; dyslipidemia; HIGH-DENSITY-LIPOPROTEIN; CATASTROPHIC ANTIPHOSPHOLIPID SYNDROME; RISK-FACTORS; ANTICARDIOLIPIN ANTIBODIES; CARDIOVASCULAR-DISEASE; RHEUMATOID-ARTHRITIS; APOLIPOPROTEIN A1; ATHEROSCLEROSIS; AUTOIMMUNITY; CHOLESTEROL;

D O I：

10.1016/j.autrev.2007.11.016

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A growing body of evidences reinforces the close link between systemic lupus erythematosus (SLE) and atherosclerosis which is due to traditional and nontraditional risk factors for cardiovascular diseases. It is now recognized that SLE has a particular pattern of dyslipoproteinemia characterized by low HDL levels and increased triglycerides, which is aggravated by flares. Multiple mechanisms can induce an altered lipoprotein metabolism in SLE such as cytokines produced during systemic inflammation, autoantibodies and therapy. (C) 2007 Elsevier B.V. All rights reserved.

引用

页码：246 / 250

页数：5

共 41 条

[1] Familial clustering of autoimmune diseases in patients with type 1 diabetes mellitus [J].