Immune Reconstitution Syndrome After Voriconazole Treatment for Cryptococcal Meningitis in a Liver Transplant Recipient

被引：19

作者：

Crespo, Gonzalo ^{[1
]}

Cervera, Carlos ^{[2
]}

Michelena, Javier ^{[1
]}

Marco, Francesc ^{[3
]}

Moreno, Asuncion ^{[2
]}

Navasa, Miquel ^{[1
]}

机构：

[1] Hosp Clin Barcelona, Liver Unit, Inst Malalties Digest, Ctr Invest Biomed Red Enfermedades Hepat & Digest, Barcelona 08036, Spain

[2] Hosp Clin Barcelona, Dept Infect Dis, Barcelona 08036, Spain

[3] Hosp Clin Barcelona, Dept Microbiol, Ctr Diagnost Biomed, Inst Invest Biomed August Pi & Sunyer, Barcelona 08036, Spain

来源：

LIVER TRANSPLANTATION | 2008年 / 14卷 / 11期

关键词：

D O I：

10.1002/lt.21601

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

A new entity that comprises symptomatic worsening of an infectious or inflammatory process despite appropriate treatment was described a few years ago in human immunodeficiency virus-infected patients receiving highly active antiretroviral therapy. This entity was defined as immune reconstitution syndrome, and it is believed to result from an intense inflammatory reaction in patients with an appropriately treated infection who recover immunological status. Recently, immune reconstitution syndrome has also been described in transplant recipients, although information is scarce because of its low incidence. Here we describe a new case of immune reconstitution syndrome in a liver transplant recipient after successful treatment of cryptococcal meningitis. Liver Transpl 14:1671-1674, 2008. (C) 2008 AASLD.

引用

页码：1671 / 1674

页数：4

共 20 条

[1] Inflammatory reactions in HIV-1-infected persons after initiation of highly active antiretroviral therapy [J].

DeSimone, JA ;

Pomerantz, RJ ;

Babinchak, TJ .

ANNALS OF INTERNAL MEDICINE, 2000, 133 (06) :447-454

[2] Cytomegalovirus-associated chorioretinitis after liver transplantation:: case report and review of the literature [J].

Egli, A. ;

Bergamin, O. ;

Muellhaupt, B. ;

Seebach, J. D. ;

Mueller, N. J. ;

Hirsch, H. H. .

TRANSPLANT INFECTIOUS DISEASE, 2008, 10 (01) :27-43

[3] Withdrawal of cyclosporine or prednisone six months after kidney transplantation in patients on triple drug therapy:: A randomized, prospective, multicenter study [J].

Gregoor, PJHS ;

De Sévaux, RGL ;

Ligtenberg, G ;

Hoitsma, AJ ;

Hené, RJ ;

Weimar, W ;

Hilbrands, LB ;

Van Gelder, T .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2002, 13 (05) :1365-1373

[4] Calcineurin inhibitor withdrawal and conversion to mycophenolate mofetil and steroids in cardiac transplant recipients with chronic renal failure:: a word of caution [J].

Groetzner, Jan ;

Kaczmarek, Ingo ;

Schirmer, Johannes ;

Uberfuhr, Peter ;

Gulbins, Helmut ;

Daebritz, Sabine ;

Meiser, Bruno ;

Reichart, Bruno .

CLINICAL TRANSPLANTATION, 2008, 22 (05) :587-593

[5] Cryptococcal meningitis after liver transplantation [J].

Jabbour, N ;

Reyes, J ;

Kusne, S ;

Martin, M ;

Fung, J .

TRANSPLANTATION, 1996, 61 (01) :146-149

[6]

Lesho Emil, 2006, Expert Rev Anti Infect Ther, V4, P469, DOI 10.1586/14787210.4.3.469

[7] Voriconazole concentrations in the cerebrospinal fluid and brain tissue of guinea pigs and immunocompromised patients [J].

Lutsar, I ;

Roffey, S ;

Troke, P .

CLINICAL INFECTIOUS DISEASES, 2003, 37 (05) :728-732

[8] Rates of antifungal resistance among Spanish clinical isolates of Cryptococcus neoformans var. neoformans [J].

Perkins, A ;

Gomez-Lopez, A ;

Mellado, E ;

Rodriguez-Tudela, JL ;

Cuenca-Estrella, M .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2005, 56 (06) :1144-1147

[9] Paradoxical worsening of tuberculosis in a heart-lung transplant recipient [J].

Place, S. ;

Knoop, C. ;

Remmelink, M. ;

Baldassarre, S. ;

Van Vooren, J.-P. ;

Jacobs, F. ;

Mascart, F. ;

Estenne, M. .

TRANSPLANT INFECTIOUS DISEASE, 2007, 9 (03) :219-224

[10] Incidence and risk factors for immune reconstitution inflammatory syndrome in an ethnically diverse HIV type 1-infected cohort [J].

Ratnam, I ;

Chiu, C ;

Kandala, NB ;

Easterbrook, PJ .

CLINICAL INFECTIOUS DISEASES, 2006, 42 (03) :418-427

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