The vascular endothelial barrier - Selective retention of lipoproteins

被引：65

作者：

Nordestgaard, BG ^{[1
]}

机构：

[1] HERLEV UNIV HOSP,DEPT CLIN BIOCHEM,DK-2730 HERLEV,DENMARK

来源：

CURRENT OPINION IN LIPIDOLOGY | 1996年 / 7卷 / 05期

关键词：

D O I：

10.1097/00041433-199610000-00002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

New experimental evidence in vivo suggests that, upon entrance into the arterial intima, IDL and VLDL become trapped at least to the same extent as LDL, and that lipoprotein(a) in normal arteries becomes trapped to the same extent as LDL. In the injured vessel, however, lipoprotein(a) seems to be trapped more than LDL. Further, new evidence also suggests that mildly oxidized LDL may circulate in plasma for a period long enough to enter, accumulate, and be degraded in the arterial intima in preference to normal LDL.

引用

页码：269 / 273

页数：5

共 24 条

[1] PRESENCE OF A MODIFIED LOW-DENSITY LIPOPROTEIN IN HUMANS [J].

AVOGARO, P ;

BON, GB ;

CAZZOLATO, G .

ARTERIOSCLEROSIS, 1988, 8 (01) :79-87

[2] LUMINAL SURFACE CONCENTRATION OF LIPOPROTEIN (LDL) AND ITS EFFECT ON THE WALL UPTAKE OF CHOLESTEROL BY CANINE CAROTID ARTERIES [J].

DENG, XY ;

MAROIS, Y ;

HOW, T ;

MERHI, Y ;

KING, M ;

GUIDOIN, R .

JOURNAL OF VASCULAR SURGERY, 1995, 21 (01) :135-145

[3] RENAL AND SYSTEMIC TRANSVASCULAR ALBUMIN LEAKAGE IN SEVERE ATHEROSCLEROSIS [J].

JENSEN, JS .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1995, 15 (09) :1324-1329

[4]

JUUL K, 1996, IN PRESS CIRCULATION

[5] EXTRACELLULAR MAST-CELL GRANULES CARRY APOLIPOPROTEIN B-100-CONTAINING LIPOPROTEINS INTO PHAGOCYTES IN HUMAN ARTERIAL INTIMA - FUNCTIONAL COUPLING OF EXOCYTOSIS AND PHAGOCYTOSIS IN NEIGHBORING CELLS [J].

KAARTINEN, M ;

PENTTILA, A ;

KOVANEN, PT .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1995, 15 (11) :2047-2054

[6] LIPOPROTEIN (A) DISPLAYS INCREASED ACCUMULATION COMPARED WITH LOW-DENSITY-LIPOPROTEIN IN THE MURINE ARTERIAL-WALL [J].

KREUZER, J ;

LLOYD, MB ;

BOK, D ;

FLESS, GM ;

SCANU, AM ;

LUSIS, AJ ;

HABERLAND, ME .

CHEMISTRY AND PHYSICS OF LIPIDS, 1994, 67-8 :175-190

[7] LIPOPROTEIN (A) AND CORONARY HEART-DISEASE [J].

MAHER, VMG ;

BROWN, BG .

CURRENT OPINION IN LIPIDOLOGY, 1995, 6 (04) :229-235

[8] CHYLOMICRONS OR THEIR REMNANTS PENETRATE RABBIT THORACIC AORTA AS EFFICIENTLY AS DO SMALLER MACROMOLECULES, INCLUDING LOW-DENSITY-LIPOPROTEIN, HIGH-DENSITY-LIPOPROTEIN, AND ALBUMIN [J].

MAMO, JCL ;

WHEELER, JR .

CORONARY ARTERY DISEASE, 1994, 5 (08) :695-705

[9] Specific accumulation of lipoprotein(a) in balloon-injured rabbit aorta in vivo [J].

Nielsen, LB ;

Stender, S ;

Kjeldsen, K ;

Nordestgaard, BG .

CIRCULATION RESEARCH, 1996, 78 (04) :615-626

[10] Transfer of low density lipoprotein into the arterial wall and risk of atherosclerosis [J].

Nielsen, LB .

ATHEROSCLEROSIS, 1996, 123 (1-2) :1-15

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