Chemical analysis and antioxidant activity in vitro of a β-D-glucan isolated from Dictyophora indusiata

被引：124

作者：

Deng, Chao ^{[2
]}

Hu, Zhun ^{[2
]}

Fu, Haitian ^{[2
]}

Hu, Minghua ^{[3
]}

Xu, Xin ^{[1
]}

Chen, Jinghua ^{[2
]}

机构：

[1] Wuxi 2 Peoples Hosp, Wuxi 214002, Peoples R China

[2] Jiangnan Univ, Sch Med & Pharmaceut, Wuxi 214122, Peoples R China

[3] Infinitus China Co Ltd, Guangzhou 510665, Peoples R China

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2012年 / 51卷 / 1-2期

关键词：

Dictyophora indusiata; beta-D-Glucan; Antioxidant activity; BRANCHED (1->3)-BETA-D-GLUCAN; POLYSACCHARIDES; CONFORMATION; EXTRACT;

D O I：

10.1016/j.ijbiomac.2012.05.001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

In this study, a water-soluble polysaccharide (PPS) from Dictyophora indusiata was purified and investigated through a combination of gel chromatography (Sephadex G-200), infrared (IR) spectroscopy, and gas chromatography-mass spectrometry (GC-MS). The results indicated that PPS has a backbone of beta-conformation, mainly consist of glucose (98.58%). And the antioxidant activities of PPS were investigated in vitro including reducing power, hydroxyl assay, superoxide radical assay and DPPH scavenge activity. The results showed that PPS has antioxidant activities in all these assay systems, suggesting it may be explored as a novel natural antioxidant with potential therapeutic properties in mammalian systems. (c) 2012 Elsevier B.V. All rights reserved.

引用

页码：70 / 75

页数：6

共 25 条

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[2]

Structure elucidation and antioxidant activity of a novel polysaccharide isolated from Tricholoma matsutake [J].