Keep PNUTS in Your Heart

被引：16

作者：

Loffredo, Francesco S.

Pancoast, James R.

Lee, Richard T.

机构：

[1] Brigham & Womens Hosp, Harvard Stem Cell Inst, Brigham Regenerat Med Ctr, Boston, MA 02115 USA

[2] Brigham & Womens Hosp, Dept Med, Div Cardiovasc, Boston, MA 02115 USA

来源：

CIRCULATION RESEARCH | 2013年 / 113卷 / 02期

关键词：

MYOCARDIAL-INFARCTION; MICRORNAS; APOPTOSIS; P53; PHOSPHATASE; REGULATOR; RENEWAL; GROWTH;

D O I：

10.1161/CIRCRESAHA.113.301933

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Aging is a major factor in many cardiovascular diseases. The molecular factors that regulate age-related changes in cardiac physiology and contribute to the increased cardiovascular risk in the elderly are not fully understood. A study recently published in Nature suggests a specific role for microRNAs (miRNAs) in regulating cardiac aging and function, challenging the concept that aging is an inevitable process in the heart.

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收藏

页码：97 / 99

页数：3

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