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Infectious Agents and Colorectal Cancer: A Review of Helicobacter pylori, Streptococcus bovis, JC Virus, and Human Papillomavirus

被引：108
作者：
Burnett-Hartman, Andrea N. [1 ,2 ]
Newcomb, Polly A. [2 ]
Potter, John D. [2 ]
机构：
[1] Univ Washington, Sch Publ Hlth & Community Med, Dept Epidemiol, Seattle, WA 98109 USA
[2] Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA
来源：
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION | 2008年 / 17卷 / 11期
关键词：
D O I：
10.1158/1055-9965.EPI-08-0571
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Based on the high volume of bacteria and viruses that the intestine is exposed to and the importance of infectious agents in some gastrointestinal and anogenital cancers, it is not surprising the many studies have evaluated the association between colorectal cancer and infectious agents. This review highlights investigations of four agents in relation to colorectal cancer. Helicobacter pylori, Streptococcus bovis, JC virus, and human papillomavirus have all been evaluated as possible etiologic agents for colorectal cancer. For each of these agents, a review of possible mechanisms for carcinogenesis and epidemiologic evidence is discussed, and future directions for research are proposed. (Cancer Epidemiol Biomarkers Prev 2008;17(11):2970-9)
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页码：2970 / 2979
页数：10
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