Nematophin, a novel antimicrobial substance produced by Xenorhabdus nematophilus (Enterobactereaceae)

被引：92

作者：

Li, JX

Chen, GH

Webster, JM

机构：

[1] Department of Biological Sciences, Simon Fraser University, Vancouver

来源：

CANADIAN JOURNAL OF MICROBIOLOGY | 1997年 / 43卷 / 08期

关键词：

nematophin; symbiotic bacteria; Xenorhabdus nematophilus; antibiotic;

D O I：

10.1139/m97-110

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new antibiotic, nematophin, was isolated from strain BCl of Xenorhabdus nematophilus and detected in all strains of X. nematophilus studied. Its structure is fully established as 3-indoleethyl (3'-methyl-2'-oxo)pentanamide by extensive spectroscopic study. The production of nematophin is affected by the strain type and culture conditions. The compound shows strong in vitro bioactivity against a series of fungal and bacterial species.

引用

页码：770 / 773

页数：4

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