Development and application of a carbonyl-13C-enriched backbone amide linker for solid-phase reaction monitoring

被引：10

作者：

Jamieson, C ^{[1
]}

Congreve, MS ^{[1
]}

Hewitt, PR ^{[1
]}

Scicinski, JJ ^{[1
]}

Ley, SV ^{[1
]}

机构：

[1] Univ Cambridge, GlaxoSmithKline R&D, Dept Chem, Cambridge CB2 1EW, England

来源：

JOURNAL OF COMBINATORIAL CHEMISTRY | 2001年 / 3卷 / 04期

关键词：

D O I：

10.1021/cc010012w

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The synthesis and application of a carbonyl-C-13 backbone amide linker are described. The labeled unit is conveniently mixed with commercial resins, providing a rapid means of monitoring chemistry performed with this linker on solid support using conventional C-13 NMR methods.

引用

页码：397 / 399

页数：3

共 53 条

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