High throughput on-bead monitoring of solid phase reactions by diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS)

被引:39
作者
Chan, TY
Chen, R
Sofia, MJ
Smith, BC
Glennon, D
机构
[1] TRANSCELL TECHNOL INC,MONMOUTH JCT,NJ 08852
[2] SPECTROS INSTRUMENTS INC,SHREWSBURY,MA 01545
[3] MIDAC CORP,IRVINE,CA 92714
关键词
D O I
10.1016/S0040-4039(97)00496-6
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Diffuse Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS) provides a method for high throughout on-bead monitoring of solid phase reactions. DRIFTS spectra can be acquired with a few milligrams of resin sample and sample preparation is not required. Analysis time is short and an automated DRIFTS accessory is commercially available. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码:2821 / 2824
页数:4
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