Muliticomponent Reactions for the Synthesis of Heterocycles

被引：465

作者：

Jiang, Bo ^{[1
]}

Rajale, Trideep ^{[2
]}

Wever, Walter ^{[2
]}

Tu, Shu-Jiang ^{[1
]}

Li, Guigen ^{[2
]}

机构：

[1] Xuzhou Normal Univ, Sch Chem & Chem Engn, Xuzhou 221116, Jiangsu, Peoples R China

[2] Texas Tech Univ, Dept Chem & Biochem, Lubbock, TX 79409 USA

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2010年 / 5卷 / 11期

基金：

美国国家科学基金会;

关键词：

domino reactions; green chemistry; heterocycles; microwave irradiation; multicomponent reactions; MICROWAVE-ASSISTED SYNTHESIS; ONE-POT; EFFICIENT SYNTHESIS; MULTICOMPONENT REACTIONS; 3-COMPONENT SYNTHESIS; DOMINO REACTIONS; TETRASUBSTITUTED IMIDAZOLES; REGIOSELECTIVE SYNTHESIS; CONVENIENT SYNTHESIS; SELECTIVE FORMATION;

D O I：

10.1002/asia.201000310

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Multicomponent domino reactions (MDRs) serve as a rapid and efficient tool for the synthesis of versatile heterocycles, particularly those containing structural diversity and complexity, by a one-pot operation. These reactions can dramatically reduce the generation of chemical wastes, costs of starting materials, and the use of energy and manpower. Moreover, the reaction period can be substantially shortened. This Review covers recent advances on multicomponent domino reactions for the construction of five-, six-, and seven-membered heterocyclic skeletons and their multicyclic derivatives.

引用

页码：2318 / 2335

页数：18

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