Characterization of the 6′-N-aminoglycoside acetyltransferase gene aac(6′)-Iq from the integron of a natural multiresistance plasmid

被引:19
作者
Centrón, D
Roy, PH
机构
[1] Univ Buenos Aires, Fac Med, Dept Microbiol, RA-1121 Buenos Aires, DF, Argentina
[2] Univ Laval, Fac Sci & Genie, Dept Biochim, St Foy, PQ G1K 7P4, Canada
[3] CHU Laval, Ctr Rech, Ctr Rech Infectiol, Quebec City, PQ G1V 4G2, Canada
关键词
D O I
10.1128/AAC.42.6.1506
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The nucleotide sequence of a newly identified amikacin resistance gene, anc(6')-Iq (551 bp), is reported. It has 68.4 and 94.4% homology with the aac(6')-Ia gene and the recently described aac(6')-Ip gene, respectively. Analysis of its flanking sequences indicated that it is in the first cassette of a class I integron and has an attC site (59-base element) 108 bp in length.
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页码:1506 / 1508
页数:3
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