Medical exposure to ionising radiation and the risk of brain tumours:: Interphone study group, Germany

被引:49
作者
Blettner, Maria
Schlehofer, Brigitte
Samkange-Zeeb, Florence
Berg, Gabriele
Schlaefer, Klaus
Schuz, Joachim
机构
[1] Johannes Gutenberg Univ Mainz, Inst Med Biostat Epidemiol & Informat, D-55131 Mainz, Germany
[2] German Canc Res Ctr, Environm Epidemiol Unit, Heidelberg, Germany
[3] Univ Bielefeld, Fac Publ Hlth, Dept Epidemiol & Int Publ Hlth, Bielefeld, Germany
[4] Danish Canc Soc, Inst Canc Epidemiol, Copenhagen, Denmark
关键词
ionising radiation; brain tumours; risk factors; aetiology; epidemiology; case-control study;
D O I
10.1016/j.ejca.2007.06.020
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: The role of exposure to low doses of ionising radiation in the aetiology of brain tumours has yet to be clarified. The objective of this study was to investigate the association between medically or occupationally related exposure to ionising radiation and brain tumours. Methods: We used self-reported medical and occupational data collected during the German part of a multinational case-control study on mobile phone use and the risk of brain tumours (Interphone study) for the analyses. Results: For any exposure to medical ionising radiation we found odds ratios (ORs) of 0.63 (95% confidence interval (CI) = 0.48-0.83), 1.08 (95% CI = 0.80-1.45) and 0.97 (95% CI = 0.54-1.75) for glioma, meningioma and acoustic neuroma, respectively. Elevated ORs were found for meningioma (OR 2.32, 95% CI: 0.90-5.96) and acoustic neuroma (OR 6.45, 95% CI: 0.62-67.16) for radiotherapy to the head and neck regions. Conclusion: We did not find any significant increased risk of brain tumours for exposure to medical ionising radiation. (C) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1990 / 1998
页数:9
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