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Hearts late after Fontan operation have normal mass, normal volume, and reduced systolic function - A magnetic resonance imaging study
被引:52
作者:
Eicken, A
Fratz, S
Gutfried, C
Balling, G
Schwaiger, M
Lange, R
Busch, R
Hess, J
Stern, H
机构:
[1] Tech Univ Munich, Deutsch Herzzentrum, Dept Pediat Cardiol & Congenital Heart Dis, D-80636 Munich, Germany
[2] Tech Univ Munich, Dept Nucl Med, D-80636 Munich, Germany
[3] Tech Univ Munich, Deutsch Herzzentrum, Dept Thorac & Cardiovasc Surg, D-80636 Munich, Germany
[4] Tech Univ Munich, Inst Med Stat & Epidemiol, D-80636 Munich, Germany
关键词:
D O I:
10.1016/S0735-1097(03)00986-0
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
OBJECTIVES The purpose of this study was to assess ventricular mass, volume, and systolic function in patients late after Fontan operation by cardiac magnetic resonance imaging. BACKGROUND An assessment of determinants for ventricular function in post-Fontan patients was intended. METHODS Twenty-three unselected patients (9 female, 14 male) at a median age of 19.4 years (range, 7.8 to 31.3 years), at a median time of 10.5 years (range, 4.1 to 18 years) after Fontan operation were studied. A standard 1.5-T scanner was used, and analysis was performed using dedicated software. Ten healthy volunteers (median age 26.4, range 18 to 39.3 years) served as the control group. RESULTS Median end-systolic mass index was 72.2 g/m(2) (range, 43 to 138 g/m(2)) and 86.6 g/m(2) (range, 52 to 123 g/m(2)) in the control group (p = NS). Median end-diastolic ventricular volume was 64 ml/m(2) (range, 32 to 117 ml/m(2)) compared with 67.7 ml/m(2) (range, 59 to 75 ml/m(2)) in the control group (p = NS). Median ejection fraction was 49.3% (range, 20% to 63%) compared with 64.8% (range, 57% to 79%) in normals (p = 0.00001). CONCLUSIONS We conclude that long-term survivors of a Fontan operation have normal ventricular mass, normal volume, but reduced systolic ventricular function. (C) 2003 by the American College of Cardiology Foundation.
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页码:1061 / 1065
页数:5
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