Principles of and Advances in Percutaneous Ablation

被引：684

作者：

Ahmed, Muneeb ^{[1
,2
]}

Brace, Christopher L. ^{[4
,5
]}

Lee, Fred T., Jr. ^{[4
,5
]}

Goldberg, S. Nahum ^{[1
,3
,6
]}

机构：

[1] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Lab Minimally Invas Tumor Therapy,Dept Radiol, Boston, MA 02215 USA

[2] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Sect Intervent Radiol,Dept Radiol, Boston, MA 02215 USA

[3] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Sect Abdominal Imaging,Dept Radiol, Boston, MA 02215 USA

[4] Univ Wisconsin, Dept Radiol, Madison, WI 53706 USA

[5] Univ Wisconsin, Dept Elect & Comp Engn, Madison, WI 53706 USA

[6] Hadassah Hebrew Univ, Med Ctr, Dept Radiol, Div Image Guided Therapy, Jerusalem, Israel

来源：

RADIOLOGY | 2011年 / 258卷 / 02期

关键词：

RADIOFREQUENCY THERMAL ABLATION; SMALL HEPATOCELLULAR-CARCINOMA; ETHANOL INJECTION THERAPY; VIVO PORCINE LIVER; INTRATUMORAL LIPOSOMAL DOXORUBICIN; INTERNALLY COOLED ELECTRODE; LASER-INDUCED THERMOTHERAPY; FINITE-ELEMENT-ANALYSIS; ACETIC-ACID INJECTION; RENAL-CELL CARCINOMA;

D O I：

10.1148/radiol.10081634

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Image-guided tumor ablation with both thermal and nonthermal sources has received substantial attention for the treatment of many focal malignancies. Increasing interest has been accompanied by continual advances in energy delivery, application technique, and therapeutic combinations with the intent to improve the efficacy and/or specificity of ablative therapies. This review outlines clinical percutaneous tumor ablation technology, detailing the science, devices, techniques, technical obstacles, current trends, and future goals in percutaneous tumor ablation. Methods such as chemical ablation, cryoablation, high-temperature ablation (radiofrequency, microwave, laser, and ultrasound), and irreversible electroporation will be discussed. Advances in technique will also be covered, including combination therapies, tissue property modulation, and the role of computer modeling for treatment optimization. (C) RSNA, 2011

引用

页码：351 / 369

页数：19

共 152 条

[61] Combination of radiofrequency ablation with antiangiogenic therapy for tumor ablation efficacy:: Study in mice [J].