Low potential detection of NADH at titanium-containing MCM-41 modified glassy carbon electrode

被引：24

作者：

Dai, Zhihui ^{[1
]}

Lu, Guofei

Bao, Jianchun

Huang, Xiaohua

Ju, Huangxian

机构：

[1] Nanjing Normal Univ, Dept Chem, Nanjing 210097, Peoples R China

[2] Nanjing Univ, Dept Chem, Nanjing 210093, Peoples R China

[3] Nanjing Xiaozhuang Coll, Dept Chem, Nanjing 210017, Peoples R China

来源：

ELECTROANALYSIS | 2007年 / 19卷 / 05期

关键词：

NADH; Ti-MCM-41; electrocatalytic; biosensors; dehydrogenases;

D O I：

10.1002/elan.200603769

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Titanium-containing MCM-41 (Ti-MCM-41) modified glassy carbon electrode (GCE) can exhibit an excellent electrocatalytic activity towards the oxidation of beta-Nicotinamide adenine dinucleotide (NADH). A dramatic decrease in the over-voltage of NADH oxidation reaction is observed at 0.28 V (vs. SCE). The modified electrode is found to be stable and reproducible. The electrode shows a linear response for a wide range of 10 - 1200 mu M NADH and the detection limit is 8.0 mu M. Ti-MCM-41 mesoporous molecular sieves provide an efficient matrix for development of NADH biosensors and the prepared electrode not only can be used to detect the concentration of NADH in biochemical reaction, but also as the potential matrix of the construction of dehydrogenases biosensor.

引用

页码：604 / 607

页数：4

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