OCT-based arterial elastography: robust estimation exploiting tissue biomechanics

被引:75
作者
Chan, RC [1 ]
Chau, AH
Karl, WC
Nadkarni, S
Khalil, AS
Iftimia, N
Shishkov, M
Tearney, GJ
Kaazempur-Mofrad, MR
Bouma, BE
机构
[1] Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Boston, MA 02115 USA
[3] Boston Univ, Dept Elect Engn & Comp Engn, Boston, MA 02215 USA
[4] MIT, Dept Mech Engn, Cambridge, MA 02139 USA
来源
OPTICS EXPRESS | 2004年 / 12卷 / 19期
关键词
D O I
10.1364/OPEX.12.004558
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We present a novel multi-resolution variational framework for vascular optical coherence elastography (OCE). This method exploits prior information about arterial wall biomechanics to produce robust estimates of tissue velocity and strain, reducing the sensitivity of conventional tracking methods to both noise- and strain-induced signal decorrelation. The velocity and strain estimation performance of this new estimator is demonstrated in simulated OCT image sequences and in benchtop OCT scanning of a vascular tissue sample. (C) 2004 Optical Society of America.
引用
收藏
页码:4558 / 4572
页数:15
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