Synthesis of functionalized nitroarylmagnesium halides via an iodine-magnesium exchange

被引：47

作者：

Sapountzis, L ^{[1
]}

Dube, H ^{[1
]}

Lewis, R ^{[1
]}

Gommermann, N ^{[1
]}

Knochel, P ^{[1
]}

机构：

[1] Univ Munich, Dept Chem, D-81377 Munich, Germany

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 70卷 / 07期

关键词：

D O I：

10.1021/jo048132o

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various nitro-substituted aryl and heteroaryl iodides undergo an iodine-magnesium exchange reaction when treated with PhMgCl leading to nitro-containing magnesium organometallics. These Grignard reagents display an excellent stability at temperatures below -40 degrees C and do not undergo electron-transfer reactions. They react as expected with various electrophiles.

引用

页码：2445 / 2454

页数：10

共 79 条

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