METALLO-β-LACTAMASE-PRODUCING CLINICAL ISOLATES OF ACINETOBACTER SPECIES AND PSEUDOMONAS AERUGINOSA FROM INTENSIVE CARE UNIT PATIENTS OF A TERTIARY CARE HOSPITAL

被引：46

作者：

Ifran, S. ^{[1
]}

Zafar, A. ^{[1
]}

Guhar, D. ^{[1
]}

Ahsan, T. ^{[1
]}

Hasan, R. ^{[1
]}

机构：

[1] Aga Khan Univ & Hosp, Dept Pathol & Microbiol, Clin Lab, Karachi, Pakistan

来源：

INDIAN JOURNAL OF MEDICAL MICROBIOLOGY | 2008年 / 26卷 / 03期

关键词：

Acinetobacter spp; metallo-beta-lactamase; Pseudomonas aeruginosa;

D O I：

10.4103/0255-0857.42035

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

Prompt detection of metallo-beta-lactamase (MBL) producing isolates is necessary to prevent their dissemination. Frequency of MBLs producing strains among multidrug resistant (MDR) Acinetobacter species and Pseudomonas aeruginosa was evaluated in critical care patients using imipenem-EDTA disk method. One hundred MDR Acinetobacter spp. and 42 Pseudomonas aeruginosa were checked for MBL production, from January to June 2001. MBL was produced by 96.6 % of imipenem-resistant Acinetobacter isolates, whereas 100 imipenem-resistant Pseudomonas aeroginosa isolates were MBL producers. Carbapenem resistance in MDR Acinetobacter spp. and Pseudomonas aeruginosa isolates in this study was due to MBLs. This calls for strict infection control measures to prevent further dissemination.

引用

页码：243 / 245

页数：3

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