Characterization of Extensively Drug-Resistant Mycobacterium tuberculosis Clinical Isolates in China

被引：43

作者：

Sun, Zhaogang ^{[1
]}

Chao, Yanjie ^{[2
]}

Zhang, Xuxia ^{[1
]}

Zhang, Jianyuan ^{[1
]}

Li, Yan ^{[1
]}

Qiu, Yunqing ^{[1
]}

Liu, Yi ^{[1
]}

Nie, Lihui ^{[1
]}

Guo, Aizhen ^{[2
]}

Li, Chuanyou ^{[1
]}

机构：

[1] Beijing TB & Thorac Tumor Res Inst, Dept Bacteriol & Immunol, Beijing 101149, Peoples R China

[2] Huazhong Agr Univ, Coll Vet Med, State Key Lab Agr Microbiol, Wuhan 430070, Peoples R China

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2008年 / 46卷 / 12期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1128/JCM.00822-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Thirteen extensively drug-resistant tuberculosis isolates which were highly resistant to a broad spectrum of antituberculosis drugs were identified from 1,926 clinical isolates in China. They had highly diverse mycobacterial interspersed repetitive-unit-variable-number tandem-repeat patterns. Most, but not all, of the drug target genes had mutations contributing to resistance to the corresponding drug.

引用

页码：4075 / 4077

页数：3