Carbon nanotube substrates boost neuronal electrical signaling

被引:474
作者
Lovat, V
Pantarotto, D
Lagostena, L
Cacciari, B
Grandolfo, M
Righi, M
Spalluto, G
Prato, M
Ballerini, L
机构
[1] Dipartimento Sci Farmaceut, Trieste, Italy
[2] Univ Trieste, Physiol & Pathol Dept, Ctr Neurosci BRAIN, I-34127 Trieste, Italy
[3] Univ Ferrara, Dept Pharmaceut Sci, I-44100 Ferrara, Italy
[4] SISSA, ISAS, Neurobiol Sect, I-34014 Trieste, Italy
[5] SISSA, ISAS, Ist Nazl Fis Mat Unit, I-34014 Trieste, Italy
[6] INSTM, Dipartimento Sci Farmaceut, Unita Trieste, Trieste, Italy
关键词
D O I
10.1021/nl050637m
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We demonstrate the possibility of using carbon nanotubes (CNTs) as potential devices able to improve neural signal transfer while supporting dendrite elongation and cell adhesion. The results strongly suggest that the growth of neuronal circuits on a CNT grid is accompanied by a significant increase in network activity. The increase in the efficacy of neural signal transmission may be related to the specific properties of CNT materials, such as the high electrical conductivity.
引用
收藏
页码:1107 / 1110
页数:4
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